王凡龙，男，博士，副研究员。主要从事作物与真菌病害互作机制解析、真菌毒素解毒基因挖掘与应用等研究，以第一作者或参与作者在Nature Communications、Cell Reports、elife、Plant Biotechnology Journal等期刊发表论文10余篇，主持国家级和省部级项目3项，获国家发明专利授权2项。
教育经历
2015.09-2021.12：bevictor1946韦德官网，博士，导师：裴炎 教授
2012.09-2015.06：石河子大学，硕士，导师：孙杰 教授
2008.09-2012.06：石河子大学，学士
工作经历
2025.07-至今：bevictor1946韦德官网，副研究员
2022.01-2025.06：bevictor1946韦德官网，讲师
研究方向
1）植物与病原真菌互作机理
2）植物解毒真菌毒素的途径及分子机制
主持项目
1）国家自然科学基金青年项目，32202320，ALA1的N端与C端在起始囊泡包装真菌毒素DON并转运至液泡中的功能，2023.1-2025.12，30万元
2）重庆市自然科学基金面上项目，CSTB2022NSCQ-MSX0625,植物P4-ATPases解毒真菌毒素DON与T-2提高玉米抗禾谷镰刀菌的功能研究，2022.8-2024.8，10万元
3）bevictor1946韦德官网基本科研业务费，SWU-KQ22011，植物ALA1转运并解毒真菌毒素的分子机制，2022.1-2023.12，10万元
4）重庆市研究生科研创新项目，CYB17072，P4-ATPases介导的植物对大丽轮枝菌解毒机理研究，2017.5-2019.5，2万
代表性论文（*通讯作者；#共同第一作者）
1)Fanlong Wang, Mingliang Qiu, Lei Hou, Xianbi Li, Hui Ren, Jingxin Zhuo, Haoru Liu, Yujie Li, Yang Yang, Xingying Yan, Mi Zhang, Dan Jin, Ting Lan, Jianyan Zeng, Yanhua Fan, Yang Yuan, Zhengqiang Ma and Yan Pei*. N terminus and C terminus of Arabidopsis P4-ATPase AtALA1 facilitate the detoxification of the mycotoxin deoxynivalenol in wheat. Cell Reports, 2025, 44, 115641.
2)Fanlong Wang, Xianbi Li, Yujie Li, Jing Han, Yang Chen, Jianyan Zeng, Mei Su, Jingxin Zhuo, Hui Ren, Haoru Liu, Lei Hou, Yanhua Fan, Xingying Yan, Shuiqing Song, Juan Zhao, Dan Jin, Mi Zhang, and Yan Pei*. Arabidopsis P4 ATPases-mediated cell detoxification confers resistance to Fusarium graminearum and Verticillium dahliae. Nature Communications, 2021, 12: 6426.
3)Fanlong Wang, Mingliang Qiu, Xiaoxia Yao, Jiancong Li, Hui Ren, Mei Su, Jiaohuan Shen, Caiwang Li, Qian Jiang, Zixuan Zhang, Yundi Li, Jiyu Tang, Xianbi Li, Yanhua Fan and Yan Pei*. Arabidopsis P4-ATPases ALA1 and ALA7 Enhance Resistance to Verticillium dahliae via Detoxifying Vd-Toxins. Biology-Basel, 2025, 14:595.
4)Yujie Li#, Hui Ren#, Fanlong Wang, Jianjun Chen, Lian Ma, Yang Chen, Xianbi Li, Yanhua Fan, Dan Jin, Lei Hou, Yonghong Zhou, Nemat O Keyhani, Yan Pei*. Cell detoxification of secondary metabolites by P4-ATPase-mediated vesicle transport. eLife, 2023, 12: e79179.
5)Xiaoyan Ding#, Xianbi Li#, Lei Wang, Jianyan Zeng, Liang Huang, Li Xiong, Shuiqing Song, Juan Zhao, Lei Hou, Fanlong Wang, Yan Pei*. Sucrose enhanced reactive oxygen species generation promotes cotton fiber initiation and secondary cell wall deposition. Plant Biotechnology Journal, 2021, 19(6), 1092.
6)Fan Xu#, Li Huang#, Junyao Wang, Caixia Ma, Yingqing Tan, Fanlong Wang, Yanhua Fan, Ming Luo*. Sphingolipid synthesis inhibitor fumonisin B1 causes verticillium wilt in cotton. Journal of Integrative Plant Biology, 2022, 64(4): 836-842.
7)Jianyan Zeng, Xingying Yan, Wenqin Bai, Mi Zhang, Yang Chen, Xianbi Li, Lei Hou, Juan Zhao, Xiaoyan Ding, Ruochen Liu, Fanlong Wang, Hui Ren, Jingyi Zhang, Bo Ding, Haoru Liu, Yuehua Xiao, and Yan Pei*. Carpel-specific downregulation of GhCKXs in cotton significantly enhances seed and fiber yield. Journal of Experimental Botany, 2022, 73: 6758–6772.
8)Jianyan Zeng, Dan Yao, Ming Luo, Lingli Ding, Yi Wang, Xingying Yan, Shue Ye, Chuannan Wang, Yiping Wu, Jingyi Zhang, Yaohua Li, Lingfang Ran, Yonglu Dai, Yang Chen, Fanlong Wang, Hanyan Lai, Nian Liu, Nianjuan Fang, Yan Pei and Yuehua Xiao*. Fiber-specific increase of carotenoid content promotes cotton fiber elongation by increasing abscisic acid and ethylene biosynthesis. The Crop Journal, 2023, 11(3), 774-784.
9)Wanting Yu#, Yonglu Dai#, Junmin Chen, Aimin Liang, Yiping Wu, Qingwei Suo, Zhong Chen, Xingying Yan, Chuannan Wang, Hanyan Lai, Fanlong Wang, Jingyi Zhang, Qinzhao Liu, Yi Wang, Yaohua Li, Lingfang Ran, Jie Xiang, Zhiwu Pei, Yuehua Xiao* and Jianyan Zeng*. Upregulation of the glycine-rich protein-encoding gene GhGRPL enhances plant tolerance to abiotic and biotic stressors by promoting secondary cell wall development. Journal of Integrative Agriculture, 2024, 23(10), 3311-3327.
10)Yang Chen, Mi Zhang, Lei Wang, Xiaohan Yu, Xianbi Li, Dan Jin, Jianyan Zeng, Hui Ren, Fanlong Wang, Shuiqing Song, Xingying Yan, Juan Zhao, Lei Hou, Yan Pei*. GhKWL1 upregulates GhERF105 but its function is impaired by binding with VdISC1, a pathogenic effector of Verticillium dahliae. International Journal of Molecular Sciences, 2021, 22(14), 7328.
11)Jianyan Zeng, Xingying Yan, Wenqin Bai, Mi Zhang, Yang Chen, Xianbi Li, Lei Hou, Juan Zhao, Xiaoyan Ding, Ruochen Liu, Fanlong Wang, Hui Ren, Jingyi Zhang, Bo Ding, Haoru Liu, Yuehua Xiao, Yan Pei*. Carpel-specific down-regulation of GhCKXs in cotton significantly enhances seed and fiber yield. Journal of Experimental Botany, 2022, 73(19): 6758-6772.
12)Hui Ren, Xianbi Li, Yujie Li, Mengjun Li, Jiyuan Sun, Fanlong Wang, Jianyan Zeng, Yang Chen, Lei Wang, Xingying Yan, Yanhua Fan, Dan Jin, Yan Pei*. Loss of function of VdDrs2, a P4-ATPase, impairs the toxin secretion and microsclerotia formation, and decreases the pathogenicity of Verticillium dahliae. Frontiers in Plant Science, 2022, 13: 944364.
13)Wenhan Cheng, Fanlong Wang, Xinqi Cheng, Qianhao Zhu, Yuqiang Sun, Huaguo Zhu*, Jie Sun*. Polyamine and its metabolite H2O2 play a key role in the conversion of embryogenic callus into somatic embryos in upland cotton (Gossypium hirsutum L.). Frontiers in Plant Science, 2015, 6:1063.
14)Xingxin Tang, Lan Wu, Fanlong Wang, Wengang Tian, Xiaoming Hu, Shuangxia Jin, Huaguo Zhu*. Ectopic expression of GhSAMDC3 enhanced salt tolerance due to accumulated Spd content and activation of salt tolerance-related genes in Arabidopsis thaliana. DNA Cell Biology, 2021, 40(9): 1144-1157.
发明专利
1)裴炎, 王凡龙, 侯磊, 韩菁, 卓静欣, 苏梅, 李玉杰, 任慧, 宋水清. 利用AtALA1基因降低呕吐毒素含量而提高植物对禾谷镰刀菌抗性的方法, 中国, 2022.11.25, 专利号: ZL202010663567.2（已授权）
2)裴炎, 王凡龙, 侯磊, 苏梅, 卓静欣, 韩菁, 李玉杰, 陈杨, 李先碧. 利用AtALA7基因提高植物对大丽轮枝菌抗性的方法, 中国, 2022.11.25,专利号: ZL202010661773.X（已授权）
联系方式
E-mail：wfl20220116@swu.edu.cn; fanlongw2015@gmail.com
通讯地址：重庆市北碚区天生路2号bevictor1946韦德官网隆平楼